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Arrhythmias and Ion Channelopathies Causing Sudden Cardiac Death in Hispanic/Latino and Indigenous Populations
  • Mohamed Boutjdir,
  • Sahil Zaveri,
  • Mohamed Chahine
Mohamed Boutjdir
VA New York Harbor Healthcare System

Corresponding Author:[email protected]

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Sahil Zaveri
VA New York Harbor Healthcare System
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Mohamed Chahine
Institut Universitaire en Sante Mentale de Quebec
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Abstract

The limited literature and increasing interest in studies on cardiac electrophysiology, explicitly focusing on cardiac ion channelopathies and sudden cardiac death (SCD) in diverse populations, has prompted a comprehensive examination of existing research. Our review specifically targets Hispanic/Latino and Indigenous populations, which are often underrepresented in healthcare studies. This review encompasses investigations into genetic variants, epidemiology, etiologies, and clinical risk factors associated with arrhythmias in these demographic groups. The review explores the Hispanic paradox, a phenomenon linking healthcare outcomes to socioeconomic factors within Hispanic communities in the United States. Furthermore, it discusses studies exemplifying this observation in the context of arrhythmias and ion channelopathies in Hispanic populations. Current research also sheds light on disparities in overall healthcare quality in Indigenous populations. The available yet limited literature underscores the pressing need for more extensive and comprehensive research on cardiac ion channelopathies in Hispanic/Latino and Indigenous populations. Specifically, additional studies are essential to fully characterize pathogenic genetic variants, identify population-specific risk factors, and address health disparities to enhance the detection, prevention, and management of arrhythmias and SCD in these demographic groups.
Submitted to Journal of Cardiovascular Electrophysiology
28 Feb 2024Assigned to Editor
28 Feb 2024Submission Checks Completed
29 Feb 2024Reviewer(s) Assigned
11 Mar 2024Review(s) Completed, Editorial Evaluation Pending
11 Mar 2024Editorial Decision: Revise Minor
15 Mar 20241st Revision Received
18 Mar 2024Reviewer(s) Assigned
21 Mar 2024Review(s) Completed, Editorial Evaluation Pending
01 Apr 20242nd Revision Received
01 Apr 2024Submission Checks Completed
01 Apr 2024Assigned to Editor
03 Apr 2024Review(s) Completed, Editorial Evaluation Pending
03 Apr 2024Editorial Decision: Accept