Ta-Ag Coatings on TC4: A Strategy to Leverage Bioelectric
Microenvironments for Enhanced Antibacterial Activity
Abstract
Dental implant- related infections are serious complications after
surgery that can results in loosening or even complete loss of the
implant. Although endogenous electric fields (EEF) play an integral role
in the human body, current methods involving external electrical
stimulation are invasive and not suitable for clinical application. In
this study, we using DC magnetron sputtering, investigates the effects
of tantalum silver (Ta-Ag) coatings on titanium alloy (TC4) surfaces,
focusing on their potential to influnce EEF that enhances antibacterial
activity In this design, Ta-Ag configuration effectively increased the
surface potential difference of TC4, and furthermore, promoting Ta/Ag
ions release and reducing bacterial adhesion. The study concludes that
the Ta-Ag coating, particularly the TC4-Ta/Ag implant, promotes a stable
EEF, enhancing the long-term antibacterial and osteogenic properties of
implants. This work provides a promising strategy for developing
advanced implant materials with improved clinical efficacy.