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Metabolic Overload: How Modern Diets Exceed Biological Tolerances
  • James Oliver
James Oliver

Corresponding Author:[email protected]

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Abstract

Type 2 diabetes is not a genetic inevitability but a predictable failure of an overloaded system. The human insulin network,evolved for rare glucose surges from whole foods, is now trapped in perpetual overactivation by a modern diet of relentless refined carbohydrates. This chronic metabolic strain drives insulin resistance, beta-cell exhaustion, and ultimately, system collapse. Yet, this is not a personal failing-it is an environmental failure. 
By shifting the lens from blame to design mismatch, this paper reframes type 2 diabetes as the structural fatigue of metabolism, a breakdown accelerated by dietary stressors the body was never built to withstand. It applies engineering principles to explain this failure and offers actionable interventions-low-glycemic diets, pre-meal buffering, and fasting-to unload the system and restore metabolic resilience.
The solution is clear: stop forcing a precision system beyond its tolerances. Public health must move beyond symptom management and confront the root cause-the food environment that perpetuates chronic insulin overuse. Only by realigning nutrition with human design can we reverse the global metabolic disease crisis.