A 49 year-old male with severe low back pain showed multilevel disc bulges with spinal stenosis. After 18 treatments of low-frequency vibro-percussion stimulation initial VAS pain score of 9.5 reduced to 2.5 and the Rolland-Morris score of 13 reduced to 3. The MRI showed some resolution of L3-L4 and L4-L5.

Unroofed Coronary Sinus (UCS) is an uncommon congenital heart anomaly and the most unusual type of Atrial Septal Defect.This report presents a-71-year-old female with palpitation and dyspnea following an emotional stress, who was referred for ablation of typical atrial flutter.Finally diagnosed with a partially UCS causing a bidirectional shunt.

Acalvaria is a rare and lethal congenital malformation characterized by the absence of the cranial vault bones, dura mater and associated muscles with complete cranial content. We report a 5-year-old Malian girl seen at 20 months old for facial dysmorphia, hemiparesis, and a cranial bone defect that improved progressively.

Although the incidence of hematological toxicity due to FTD/TPI treatment is high, the incidence of severe adverse events has been reported to be relatively low. However, it should be noted that patients with renal impairment are prone to severe hematological adverse events.

To describe the surgical challenges, management, and value of intra-operative optical coherence tomography in a case of a bilateral Descemet Stripping Automated Endothelial Keratoplasty corneal transplantation at 17 weeks of age for the treatment of severe posterior polymorphous corneal dystrophy resulting from a de novo mutation of the OVOL2-gene.

An endoleak is a complication that can occur after an endovascular aneurysm repair. We report a rare case of ischemic lumbosacral plexopathy post embolization of type 2 endoleak, including its presentation, neurological progress, rehabilitation strategy and functional outcome.

We report an 8-year-old Afghan female with giant congenital melanocytic nevus (GCMN) which covered the entire back. The GCMN extended to anterolateral parts of the trunk surrounded by multiple satellite melanocytic nevi.

Wernicke's encephalopathy should be suspected in hemodialysis patients with appetite loss alone, with careful brain MRI analysis for detecting possible Wernicke's encephalopathy at an early stage.

Catecholaminergic Polymorphic Ventricular Tachycardia is a life-threatening disorder. The clinical diagnosis is challenging owing to the absence of electrocardiogram and overt structural heart abnormalities in the majority of patients. Approximately 35% of cases remain without a genetic etiology. Here, we identified two genes as a novel promising candidate for CPVT.

Here we present a case report of a chronic lymphoblastic leukemia-related pancytopenia patient where after treatment with Cyclosporin-A, chronic lymphoblastic leukemia has effectively remitted. To further understand the effect of Cyclosporin-A in immune micro-environment reconstruction and its anti-leukemia potential.

Liberal use of oxygen plays a significant role in exacerbating the long-term lung injuries associated in COVID-19. Hypoxemia and hypoxia are two different entities. Correcting hypoxemia without hypoxia tends to have disastrous effect and delays lung healing.

Urinary bladder cancer is frequently multifocal and has a high incidence of recurrence. Although the prostatic urethra is a frequent site of tumor relapse in patients with non-muscle-invasive bladder cancer treated with TURBT, such tumors are often underappreciated. Here we present two cases having urethral recurrence after TURBT.

Authors describe a rare case of acute adrenal infarction in pregnancy resulting in hypoadrenalism requiring hydrocortisone replacement therapy and anticoagulation with subsequent resolution of the radiological changes and complete recovery of the glucocorticoid reserve during clinical follow-up.

Treatment of recurrent ruptured aneurysms incorporating a branch vessel arising from the dome is challenging. Here, we attempted horizontal stent-assisted coil embolisation via a retrograde route from the contralateral internal carotid artery to treat a small ruptured posterior communicating artery aneurysm incorporating a foetal variant posterior cerebral artery after clipping.

In this article, we want to present a patient with Burtonian or lead line at the gum tooth line, a rare presentation of lead poisoning.

Pulmonary infections represent the major causes of morbidity and mortality in cystic fibrosis(CF). Here, we report a3-month old infant with pancreatic insufficient CF was hospitalized with positive RT-PCRtest for COVID-19. He was treated successfully. Hypertonic saline can be hypothesized as a treatment regimen against COVID-19 infection after further investigation

A 16-year-old female presented to our ED with fever and coughing of blood for 3 days. She is known to have SLE for 5 months and takes oral prednisone. She was tested positive for COVID19. She developed hypocalcemia with clinically-diagnosed massive pulmonary embolism. She was treated with heparin and recovered.

We report the case of a 48-year-old woman, a teacher, with recurrent severe dysphonia and multiple and different lesions at the same time in her vocal folds.