Hematologic malignancies are becoming more prevalent, manifesting in various clinical scenarios. Chronic myelogenous leukemia (CML) is usually diagnosed on routine complete blood count as it is typically asymptomatic. However, it can cause multiple signs and symptoms. We present a patient with appendicitis revealing CML during his workup for abdominal pain.

On magnetic resonance imaging (MRI), a butterfly lesion is most commonly described in Glioblastoma Multiforme (GBM), however we report an unusual case of Cryptococcus Meningoencephalitis with the butterfly lesion on MRI. This infection is generally diagnosed via lumbar puncture, however MRI may reveal perivascular space involvement, dilation and leptomeningeal enhancement.

The purpose of this study is to investigate the outcomes of an alternative method for large defects reconstruction after mastectomy by applying negative pressure wound therapy onto the grafts.

Injury to epicardial coronary arteries following mitral valve replacement surgery, albeit rare, could have fatal complications. In this case, we suggest conservative medical treatment as a safe approach in patients who are not suitable to undergo revascularization.

This study presents a rare case of postoperative amyloidosis of the tongue base and provides a summary of the known literature of tongue amyloidosis. The diagnosis was by physical examination, radiological findings, and histopathological Congo red stain. Bone marrow biopsy the revealed “Plasma cell myeloma” as a cause.

A man aged 60’s suffered nephrotic syndrome with IgM nephropathy seven years earlier. Four years later, immune-checkpoint inhibitors (ICPIs) were administered against metastasizing pulmonary adenocarcinoma. Sixty-two weeks after 21 ICPIs injections, the cancer vanished but nephrotic syndrome relapsed. Acute pancreatitis followed and usual interstitial pneumonia exacerbated, as late-onset immune-related adverse-events.

We present three cases of impetigo and one case of bullous pemphigoid neonatorum that benefited from the homeopathic remedy Antimonium crudum, which has a wide spectrum of dermatological applications when prescribed according to symptom similarity. Further larger clinical studies are necessary to establish its role in pediatric dermatology.

Incidentally diagnosed, asymptomatic, paranasal fungus ball might occasionally undergo spontaneous healing. Accurate preoperative workup may avoid unnecessary surgical or anesthesiological procedures.

Nivolumab is used for patients with recurrent/metastatic head and neck cancer resistant to platinum. We report a 76-year-old man with squamous cell carcinoma of the tongue, who developed toxic epidermal necrolysis (TEN) after nivolumab treatment. TEN is a fatal disease, and early treatment of the adverse events are important.

Histoplasmosis occurs primarily in the lungs but can disseminate in immunocompromised patients. Serology can be negative in patients with local infection, making the diagnosis challenging. Definite diagnosis is by microscopic examination of the tissue sample. We report a rare case of Histoplasma stomatitis whose lesions manifested after initiating antiretroviral therapy.

Burkitt lymphoma is a rapidly progressive disease which requires imaging, biopsy, prompt diagnosis and early aggressive chemotherapeutic treatment. We discuss a 7-year-old girl presenting with a persistent and painful unilateral swelling of the jaw. Lymphomas typically manifest as poor defined osteolytic lesions radiographically, as is presented in this case.

Arteriovenous fistulae (AVF) of the head and neck region are extremely rare, especially those that occur spontaneously. We present the case of a 58 year old female with a spontaneous postauricular AVF causing troublesome pulsatile tinnitus. In this case a simple surgical procedure completely cured the patient of her symptoms.

The authors report a case of ehrlichiosis involving a bone marrow specimen from a patient with chronic lymphocytic leukemia. Since Ehrlichia may cause a lymphohistiocytic reaction in bone marrow specimens, an infectious process may be easily confused with a lymphoid neoplasm, particularly in patients with a history of lymphoid malignancy.

We reported a case of M. szulgai respiratory infection in a 32-year-old male patient without any history of smoking, immunodeficiency syndromes, or receiving immunosuppressive medications but the patient was severely deficient in vitamin D. isoniazid, rifampin, ethambutol, clarithromycin antimicrobial agents with vitamin B6 and vitamin D.improved after 10 months.

Herniation of intra-abdominal viscera through pelvic bone defects represents an extremely uncommon complication following orthopaedic interventions in the bony pelvis. We report a rare case of acute colonic obstruction through a defect in the iliac bone, following bone graft harvesting from the iliac crest, aiming to raise clinical awareness.

A patient presented with cauda equina syndrome signs on a background of intrathecal pump implantation for chronic pain. Initial investigations were consistent with a granuloma, a common complication of intrathecal pumps. CSF cytometery revealed a lymphocytosis. This patient represented 2 months later with neck signs secondary to a B-cell-lymphoma.

The diagnosis of decompression sickness (DCS) is mostly based on clinical suspicion, and there is currently no available modality to fully confirm the diagnosis. However, the use of echocardiography in suspected DCS cases has become more common. In this case, transthoracic echocardiography (TTE) was used to detect microbubbles in the right cardiac chambers and monitor the patient after hyperbaric oxygen therapy (HBOT), suggesting the possible applicability of TTE in diagnosing and monitoring DCS patients. This report describes a 54-year-old Fisherman who was referred to the emergency department with dyspnea and mild confusion after a rapid ascent of a saturation dive at 50 m sea depth. After the initial evaluation, he was assessed using TTE to exclude the presence of structural heart disease, where it surprisingly showed spontaneous echo contrast inside the right cardiac chambers similar to agitated saline echo testing. The patient was then admitted for HBOT and follow-up; rapid improvement was noticed after the first HBOT session and the TTE findings were fully resolved. TTE could be considered in the initial workup when DCS is suspected, and it might have a role in monitoring DCS patients if echocardiographic findings of bubble formation were documented in the pre-hyperbaric therapy settings.

Esophageal perforation is most commonly caused by endoscopic instrumentation of the upper GI tract and most commonly presents with chest pain in more than 70% of patients, vomiting, and subcutaneous emphysema.