A document by Qingrun Zhu. Click on the document to view its contents.

Presumed first episode of non-convulsive status epilepticus as the cause of postoperative disorder of consciousness following the completion of general anesthesia: A case report

A document by Mukesh Bhatta. Click on the document to view its contents.

Hemophagocytic syndrome (HPS), also known as hemophagocytic lymphohistiocytosis (HLH), is a group of syndromes in which multiple pathogenic factors lead to the proliferation of activated lymphocytes and histiocytes that secrete large amounts of inflammatory cytokines[[1]](#ref-0001).HLH is a multi-organ hyperinflammatory syndrome caused by the secretion of large amounts of inflammatory cytokines from

A document by Ananda Aryal. Click on the document to view its contents.

A Case of Leukemia Cutis Showing Annular Erythema during the Course of Philadelphia Chromosome-Positive Acute B-lymphoblastic LeukemiaHizuru Tomita, MD1, Yoshimasa Nobeyama, MD1, You Sakayori, MD2, Rika Matsumoto, MD1, Satomi Chujo, MD1, Hikaru Suzuki, MD1, Akihiko Asahina, MD11. Department of Dermatology, The Jikei University School of Medicine, Tokyo, Japan2. Department of Oncology/Hematology, The Jikei University School of Medicine, Tokyo, JapanCorresponding author:Yoshimasa Nobeyama, MDDepartment of Dermatology, The Jikei University School of Medicine,3-25-8, Minato-ku, Tokyo, 105-8461, JapanE-mail: [email protected] authors received no financial support for this study.The authors have no conflicts of interest to declare.Key words: leukemia cutis, annular erythema, acute B-lymphoblastic leukemia

IntroductionCornual pregnancy is rare, accounting for approximately 2-4% of all ectopic pregnancies [1]. By definition, it refers to the implantation and development of a gestational sac at the proximal and lateral regions of the uterus (aka uterine horns or cornua). As with the majority of other types of ectopic pregnancy, cornual pregnancy diagnosis is based on clinical suspicion, β-hCG measurements and transvaginal ultrasound findings [2]. As with other types of ectopic pregnancy, cornual pregnancy is associated with severe patient morbidity and mortality [3]. Therefore, timely and accurate diagnosis is key as it directly affects treatment type and urgency. Several management options are available from the conservative (methotrexate administration and expectant management) up to the more radical side of the spectrum (cornuotomy, cornual resection, hysterectomy) [4]. Hysteroscopy is an additional option that combines effective and complete removal of the gestational sac, without severely affecting uterine anatomy, however its application usually requires imaging guidance [5].In this report, we present the case of a cornual ectopic pregnancy, which could not be diagnosed via traditional ultrasonographic imaging and instead was verified by MRI imaging. Subsequently, guided by the MRI imaging data, hysteroscopic resection and removal of all products of gestation was safely and successfully performed without any complications and with the patient making a swift recovery.

INTRODUCTION:Tuberculosis remains a significant global health burden, with central nervous system (CNS) involvement being a rare but serious manifestation. While pulmonary tuberculosis is the most common form, extrapulmonary manifestations can affect various organs and systems. The CNS involvement in developing countries constitutes nearly 10% of all tuberculosis patients [1]. Tuberculomas with compressive myelopathies without bone involvement are an even rarer occurrence. In the differential diagnosis of extensive spinal cord injuries, particularly in young patients with a history of pulmonary tuberculosis or tuberculous meningitis, it is important to consider the possibility of an intradural extramedullary tuberculoma [2].Here we will be discussing a case of intradural extramedullary tuberculosis of the thoracic spine, with progressive neurological dysfunction. Surgery aims to decompress the spinal cord and remove the tuberculoma, thereby relieving the pressure on the neural tissues and preventing further neurological deterioration [3-5]. The specific surgical technique employed depends on the location and extent of the tuberculoma.Following surgery, anti-tubercular therapy is initiated to target the underlying tuberculosis infection. This typically involves a combination of multiple anti-tuberculosis medications, such as isoniazid, rifampicin, ethambutol, and pyrazinamide [2]. The duration of anti-tubercular therapy may vary but generally lasts several months to ensure complete eradication of the infection. Continual postoperative monitoring assumes paramount importance in assessing neurological recovery and treatment response. Concurrently, physiotherapy and rehabilitation assume significance in facilitating the functional restoration and enhancing the overall quality of life [1].This report aims to discuss the diagnostic challenges, treatment strategy, and clinical outcomes, highlighting the importance of a multidisciplinary approach in managing this uncommon condition.

Background: Aberrant migration of parathyroid glands from their embryologic origin may result in undescended parathyroid glands. We present a case of an ectopic parathyroid adenoma at the level of the pyriform sinus. Methods: A 41-year-old female was evaluated for primary hyperparathyroidism. Following non-localizing ultrasound and planar sestamibi imaging, the patient underwent

Key Clinical MessageRepositioning maneuvers for benign paroxysmal positional vertigo (BPPV) designed to induce otoconial movement in one canal can trigger or treat BPPV in other canals. We suggest for standardized testing protocols to ensure correct diagnosis of BPPV.MeSH keywords : BPPV; positional vertigo; horizontal canal; positional nystagmus; case report

Subclavian Steal Syndrome

Epithelial–myoepithelial carcinoma in the parotid gland with HRAS mutation: a case reportTaisei Yasudaa, Masami Osakia, and Masahiko Sugitaniba Department of Otolaryngology-Head and Neck Surgery, Ageo Central General Hospital, Saitama, Japanb Department of Pathology, Ageo Central General Hospital, Saitama, JapanCorresponding Author:Taisei YasudaDepartment of Otolaryngology-Head and Neck SurgeryAgeo Central General Hospital1-10-10 Kashiwaza, AgeoSaitama, Japan, 362-8588Tel: +81-48-773-1111E-mail: [email protected]

A document by Nabil Dhayhi. Click on the document to view its contents.

AUTHORSDr. Saroj Poudel Clinical Pharmacist Critical Care Medicine, Nepal Mediciti Email: [email protected]. Rupak Chalise Anesthesiologist Critical Care Medicine, Nepal Mediciti Email: [email protected]. Manoj Bist Medical Officer Critical Care Medicine, Nepal Mediciti Email: [email protected]. Ashim Regmi Junior Consultant Critical Care Medicine, Nepal Mediciti Email: [email protected]. Anup Ghimire Junior Consultant Critical Care Medicine, Nepal Mediciti Email: [email protected]. Kishor Khanal Intensivist and ICU Coordinator Critical Care Medicine, Nepal Mediciti Email: [email protected]

A document by wiem ben makhlouf. Click on the document to view its contents.

Poncet’s disease: an Uncommon Presentation of a Common Disease in Sudan

A document by Harkesh Arora. Click on the document to view its contents.

Rare Association of Plasmodium Vivax Malaria with Pulmonary Thromboembolism: A Case Report Gashaw Solela1 Merga Daba2 Zerubabel Getahun2 Yared Getachew2 Dejene Girma31Department of Internal Medicine, Yekatit 12 Hospital Medical College, Addis Ababa, Ethiopia2Department of Internal Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia3Department of Internal Medicine, St. Paul’s Hospital Millennium Medical College, Addis Ababa, Ethiopia