A 58-year-old woman had gastric cancer treated with nivolumab. Her serum creatinine (Cr) increased to 5.94 mg/dL post two cycles of nivolumab and co-administered with acemetacin. A kidney biopsy showed acute tubular injury (ATI).

To describe treatment using aligners in an adult female patient with dental class II malocclusion associated with crowding. Treatment objectives were achieved in 10 months with patient satisfaction. Combining aligners with appropriate attachment location, geometry and staging are efficacious means of resolving class II malocclusion.

Hepatic arteriovenous malformation mostly occurs as a manifestation of hereditary hemorrhagic telangiectasia. Clinical symptoms include hyperpulsatile heart failure, hepatic encephalopathy, and ascites. We present a case of hepatic arteriovenous malformation and atrial septal defect causing heart failure.

Primary effusion lymphoma (PEL) is a rare non-Hodgkin lymphoma confined exclusively to body cavities without detectable tumor masses. The term PEL-like is an entity similar to PEL in clinical presentation but without relation to human herpesvirus 8 (HHV8). We report a case of HHV8- and EBV-negative primary effusion-based lymphoma.

Nodular melanoma (NM) is the third most common subtype of melanoma among African Americans (AA) behind acral lentiginous melanoma (ALM) and superficial spreading melanoma (SSM) (1, 2). This case of NM in an African American Japanese male was selected due the rare occurrence of NM in skin of color patients.

Solitary rectal ulcer syndrome (SRUS) is a rare benign rectal disorder. Due to its rare occurrence, it is not properly diagnosed and is often misdiagnosed with other diseases. In this report, we present a case of a polypoid solitary rectal ulcer presented by rectal bleeding and chronic constipation.

Myelodysplastic/ myeloproliferative overlap syndrome with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T) is a rare myeloid neoplasm showing myelodysplastic and myeloproliferative features. With extremely raised platelets, possibility of acquired Von Willebrand and risk of hemorrhage is increased. With this quandary in mind, a descriptive case and a discussion of available treatments ensues

We present a case of a 75-year-old male who presented with constipation, nausea, and vomiting for 4 days. Two diverticula were discovered 1 and 2 feet away from the duodenojejunal (DJ) junction. Due to excessive ileal edema, ileal resection, and a double barrel ileostomy was performed.

Interdisciplinary orthodontics can synchronize with tissue designing standards of periodontal regenerative medical procedure to make quick orthodontic results. Periodontally accelerated osteogenic orthodontics (PAOO) using piezosurgery, a novel approach, has found numerous applications in the field of osseous surgery. It helps to overcome the drawbacks of traditional rotary instruments.

Laryngeal venous malformations rarely but do cause airway obstruction resulting in life-threatening events. The perioperative airway management for the patients with them have not been well established. We suggest a strategy for laryngeal venous malformations management in the patients who undergo surgery in addition to planning for airway management.

a 78-year-old patient presented with a life-threatening lower gastrointestinal bleeding secondary to an aortoiliac graft-enteric fistula into the sigmoid colon on the background of an adenocarcinoma and diverticular disease. Bridging endovascular stent followed by a second-stage graft explant and autologous vein reconstruction with a simultaneous anterior resection was successfully performed.

We report two cases of previously healthy young men with COVID-19 infection who developed acute ischemic stroke due to large vessel occlusion followed by secondary events concerning for a further thromboembolic event. We hypothesize that the hypercoagulable state related to COVID-19 exacerbated the underlying hereditary thrombophilia due to MTHFR-gene mutation.

Oral chemical ulceration is a rare condition. The causes differ from misuse of dental material by dentists and over-the-counter drugs (OTC) to the herbal ingredients in our foods. This report represents a case of chemical ulceration of the mouth caused by hydraulic oil leakage inside a dental chair

Gastroenteritis can be associated with life-threatening complications like myocarditis. A 16-year-old male presented with acute myocarditis mimicking STEMI after gastroenteritis. He made an uneventful recovery after appropriate treatment. This case report highlights that clinicians should be aware of this rare, but serious, cardiac complication when treating patients with gastroenteritis.

Basal ganglia calcifications have been linked to a wide range of causes. Mostly it is an idiopathic finding, especially in elderly. Endocrinological and neurological disorders are major causatives. Hyperthyroidism was not related to this finding. We present a case of incidental basal ganglia calcification in man with Grave's disease.

Masked polycythemia vera due to iron deficiency anemiaKoma Hotta, MD1, Ryotaro Niwa, MD21Department of General Internal Medicine, Takatsuki Hospital, Osaka, Japan2Department of Hematology, Japanese Red Cross Takatsuki Hospital, Osaka, Japan

The case is a 67-year-old female with autosomal dominant polycystic kidney disease who was followed up regularly. CT scan showed a mural nodule growing over the past 4 years inside the hypodense region surrounded by hepatic cysts. Surgery was performed and the pathological diagnosis was StageⅠ gallbladder cancer.

Moebius Syndrome is a rare multifactorial condition defined by congenital complete or partial VII and VIth cranial nerves palsy and other physical abnormalities. We present the case of a 3 months old infant with Moebius sequence and breathing and eating difficulties, managed by tracheostomy and laryngoplasty.