Dynamic Temporal Signature Analysis (DTSA) offers a novel, fully automated approach to ransomware detection through the real-time monitoring of entropy changes within a system. Designed to detect ransomware activities independently of predefined signatures or human intervention, DTSA provides a solution that dynamically adjusts to the entropy deviations indicative of ransomware behaviors, capturing a wide range of patterns that elude traditional static or behavior-based detection techniques. The DTSA framework operates through a layered modular design, integrating real-time data collection, entropy monitoring, ransomware identification, and response mechanisms that collectively ensure high detection accuracy and resource efficiency across diverse ransomware profiles. Testing results demonstrate that DTSA achieves significant advances in detection precision, minimizing both false positive and false negative rates while maintaining low latency. Additionally, the adaptive thresholding mechanism enables DTSA to recalibrate autonomously, handling entropy variations across different network conditions, data packet sizes, and ransomware types, without burdening system resources. The entropy-focused approach underscores DTSA's capacity to bridge gaps in current detection methodologies by eliminating human-in-the-loop dependencies, thereby establishing an adaptable, scalable framework suitable for highdemand environments. Through validating the efficacy of entropy monitoring as a principal ransomware indicator, DTSA contributes a transformative perspective to automated cybersecurity defenses, reinforcing the viability of self-sufficient ransomware detection systems for modern digital infrastructures.