This systematic literature review (SLR) explores the broad application of Artificial Intelligence (AI) in healthcare, with a focus on integrating emotional and cognitive analysis techniques. The review aims to assess the impact of AI technologies on enhancing patient care by analyzing emotional content and supporting patient-centric applications. We examine studies that leverage AI for sentiment analysis, emotion categorization, and predictive modeling using textual data from clinical narratives, patient feedback, and online health discussions. The review identifies key advancements in emotion recognition algorithms, the synergy of cognitive and emotional analysis methods, and the development of AI-powered clinical decision support systems. These applications have significantly improved personalized therapy plans, facilitated early detection of mental health disorders, and enhanced support for clinical interventions. Despite these developments, challenges such as ethical AI implementation, patient confidentiality, and algorithmic biases remain. Nevertheless, AI's potential to transform healthcare practices is evident, promising a future of more informed, efficient, empathetic, and patient-centered healthcare. This study highlights AI's transformative impact on healthcare by providing a comprehensive overview of its role in emotional and cognitive analysis, identifying emerging trends, and advocating for the integration of AI capabilities with the human aspects of healthcare.