This comprehensive review delves into the contemporary landscape of gas flotation in the oil and gas sector, shedding light on the evolving demands for increased separation efficiency within the industry. The oil and gas sector is now placing a premium on enhanced separation efficiency, surpassing the conventional methods currently deployed. A critical exploration of the underlying principles governing the design of high-efficiency gas flotation systems is also a focal point of this review. Gas flotation, a pivotal technology within the oil and gas industry, has witnessed a significant evolution in response to the escalating need for improved separation efficiency. This heightened demand for efficiency stems from the industry’s commitment to maximizing resource recovery, minimizing environmental impact, and optimizing operational costs. As the industry continues to evolve, there is a growing recognition of the imperative to surpass existing standards and push the boundaries of gas flotation technology. The review delves into the core principles that underpin the design of high-efficiency gas flotation systems, emphasizing the need for innovative approaches to meet the industry’s escalating demands. By scrutinizing the major design principles, researchers aim to uncover novel strategies that can revolutionize gas flotation processes, paving the way for higher performance and enhanced operational outcomes. Exploring the intricate balance between operational efficiency, environmental sustainability, and cost-effectiveness, this review serves as a roadmap for industry stakeholders seeking to navigate the shifting landscape of gas flotation technology. By synthesizing the latest advancements and industry trends, the review aims to catalyze discussions and drive innovation in the realm of high-efficiency gas flotation within the oil and gas sector.This comprehensive review further illustrates how the manipulation of gas bubble size and the intricate fluid dynamics within separation vessels serve as pivotal mechanisms for augmenting oil removal efficiency within the industry. By delving into these fundamental aspects, the review elucidates how precise control over gas bubble size and a deep understanding of fluid dynamics play a central role in enhancing the effectiveness of oil removal processes. The review goes beyond theoretical discussions to showcase real-world applications of this cutting-edge gas flotation technology within the oil and gas sector. By highlighting examples of this new generation of gas flotation technology, the review offers tangible insights into how industry players are harnessing innovative approaches to optimize oil removal efficiency. These case studies and examples serve as practical illustrations of the transformative potential of leveraging advanced gas flotation techniques to achieve higher separation efficiency and operational excellence. Through a blend of theoretical underpinnings and practical demonstrations, this review bridges the gap between theory and application, providing a holistic view of the transformative impact of gas bubble size control and fluid dynamics optimization on oil removal efficiency. By showcasing how these fundamental mechanisms translate into tangible operational improvements, the review empowers industry professionals to embrace and implement the latest advancements in gas flotation technology for enhanced oil removal performance. In essence, this review not only underscores the critical roles of gas bubble size control and fluid dynamics in boosting oil removal efficiency but also offers concrete examples of how these principles are being leveraged in practice. By showcasing the innovative strides made in the realm of gas flotation technology, the review paves the way for industry stakeholders to embrace a new era of efficiency, sustainability, and performance excellence in oil and gas separation processes.