Abstract
Regulated or programmed cell death play a critical role in development
and tissue organization and function. In addition, it is intrinsically
connected with immunity and host defense. Increasing cellular and
molecular findings are changing the concept of cell death, revealing an
expanding network of regulated cell death modalities and their
biochemical programs. Likewise, recent evidences are demonstrating the
interconnection between cell death pathways and how they are involved in
different immune mechanisms. This work provides an overview of the main
cell death programs and their implication in innate immunity not only as
an immunogenic/inflammatory process, but also as an active defense
strategy during immune response and at the same time, as a regulatory
mechanism.