Changes in physiology and immune system during pregnancy and coronavirus
infection: a review
Abstract
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
the 3rd epidemic coronavirus after severe acute respiratory syndrome
coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus
(MERS-CoV). Since December 2019, the outbreak of the Coronavirus Disease
2019 (COVID-19) caused by SARS-CoV-2 has aroused great attention around
the world. Pregnant women and their fetuses have been concerned as a
high-risk population. We explained why pregnant women are susceptible to
coronavirus in terms of their adaptive changes in physiology and immune
system during pregnancy, and described the associations between maternal
clinical symptoms, perinatal outcomes and coronavirus infections.