Vitamin C is a vital nutrient that functions as an antioxidant and is important as a co-factor and regulator of several immune system pathways. The role of vitamin C in the treatment of COVID-19 is largely debatable. We conducted this meta-analysis to evaluate the efficacy and safety of vitamin C in the treatment of COVID-19. We searched several electronic databases from inception to March 2023 to retrieve randomized controlled trials on the use of Vitamin C for COVID-19. RevMan 5.4 was used to calculate risk ratios (RRs) and Mean Differences (MDs) along with confidence intervals (95% CI) using a random-effects model. We included 9 randomized controlled trials in our meta-analysis. Vitamin C did not reduce the all-cause mortality in patients with COVID-19 compared to the standard treatment [RR 0.86, 95% CI: 0.65-1.14; I 2=66%]. Vitamin C was found to be associated with an increased incidence of ventilation in COVID-19 patients when compared to standard treatment [RR 1.37, 95% CI: 1.18-1.59; I 2=58%]. There were no significant differences between both groups regarding the incidence of hospitalization [RR 1.00, 95% CI: 0.98-1.02; I 2=0%], incidence of recovery [RR 1.57, 95% CI: 0.45-5.50; I 2=52%], hospital mortality [RR 0.68, 95% CI: 0.44-1.06; I 2=0%] and length of hospital stay [MD -0.63, 95% CI: -3.04 to 1.78; I 2=81%]. Vitamin C administration did not reduce all-cause mortality in COVID-19 patients. Additional studies are required to evaluate the role of Vitamin C in the prevention and treatment of COVID-19 especially in ICU patients.

To Lyse or Not: The Role of Half-Dose Thrombolysis in Right Ventricular Clot Associated with Sub-Massive Pulmonary EmbolismNasreldin A. Hamza1, Wasfy J. Hamad1, Shamim K. Vakkulathil1, Vimalraj Sundaram1, Haidar M. Hadi2, Abdulqadir J. Nashwan3*1 Critical Care Department, Al-Khor General Hospital, Hamad Medical Corporation, Doha 3050, Qatar2 Cardiology Department, Al-Khor General Hospital, Hamad Medical Corporation, Doha 3050, Qatar3 Nursing Department, Hamad Medical Corporation, Doha 3050, Qatar*Corresponding author:Mr. Abdulqadir J. [email protected]: (+974) 66473549, P.O. Box 3050 Doha, QatarORCID: https://orcid.org/0000-0003-4845-4119E-mails: [email protected]; [email protected]; [email protected]; [email protected]; [email protected]; [email protected]

Unveiling the Enigma: Idiopathic Digital Infarction - A Case Report and Literature Review

A document by Hanan Al-Asbahi. Click on the document to view its contents.

A document by Fahmi Othman. Click on the document to view its contents.

Hepatitis A virus infection can cause extra-hepatic manifestations like myocarditis. An 8-year-old female with HAV infection presented with fever, abdominal pain, vomiting, and icterus. She developed viral myocarditis with complete AV dissociation on ECG and was treated with a temporary pacemaker, but her condition worsened, and she died.

A document by Reynaldo Jr. Balintona. Click on the document to view its contents.

Most instances of Guillain-Barré syndrome (GBS) are caused by immunological stimulation and are discovered after vaccinations for tetanus toxoid, oral polio, and swine influenza. This systematic study investigated GBS cases reported after receiving the COVID-19 vaccination.

Late Small Bowel Perforation from a Migrated Double Plastic Biliary Stent: A Case Report and a Review of Literature of 85 Cases from 2000 to 2022

Critical illness-associated cerebral microbleeds and leukoencephalopathy related to COVID-19 infection are increasingly being recognized in the literature. We report seven cases of COVID-19 with microbleeds in the juxtacortical white matter and corpus callosum and one case of leukoencephalopathy.

We present a case of a 75-year-old male who presented with constipation, nausea, and vomiting for 4 days. Two diverticula were discovered 1 and 2 feet away from the duodenojejunal (DJ) junction. Due to excessive ileal edema, ileal resection, and a double barrel ileostomy was performed.

Here we report a patient with 2q37 deletion syndrome confirmed by comparative genomic hybridization (CGH) plus single nucleotide polymorphism (SNP), who does not suffer from mental developmental abnormalities. The patient, however, does suffer from fatigue and gross motor delay, and the presence of a patent foramen ovale.