Pathological investigation and viral antigen distribution of emerging
African Swine Fever in Vietnam
Abstract
African swine fever (ASF) is emerging in Vietnam and poses a continuing
severe threat to the swine industry. A histopathological study of
clinical samples collected during the August to September 2019 outbreak
of ASF was performed to determine the characteristic lesions. We
analyzed samples from eight ASFV-infected farms. Histopathological
results revealed the characteristic lesions of the acute to the subacute
clinical form of ASF. Immunohistochemical results showed ASFV viral
antigen distribution in mononuclear cells/macrophage in various organs,
hepatocytes, and renal tubular epithelium. Molecular analysis of partial
capsid protein 72 gene revealed that ASFV strain from the eight separate
outbreaks belonged to genotype II.