Abstract
This review highlights the novelties in understanding the underlying
immunological mechanisms of drug hypersensitivity reactions (DHRs) as
well as tiny changes in clinical classification and diagnosis of DHRs
with special reference to beta-lactams (BLs) in the pediatric
population, in the last couple of years. Viral infections are very often
in children and they can provoke skin rashes which is difficult to
differentiate from DHRs. Because of that allergy to BLs in children is
overdiagnosed. The correct diagnosis of BLs allergy in children is still
an important and hot topic. In this review has been outlined the need
for correct diagnosis of BLs allergy in children as well as needed to
change the paradigm.