Clinical, radiological and laboratory characteristics and risk factors
for severity and mortality of 289 hospitalized COVID-19 patients
Abstract
Background Currently, the coronavirus disease 2019 (COVID-19) has become
pandemic globally. 10-20% of the cases are severe and more than 397,000
deaths have occurred. The risk factors for the mortality of critically
ill COVID-19 patients remain to be elucidated. Conclusions Survived
severe and non-survived COVID-19 patients had distinct clinical and
laboratory characteristics, which were separated by principle component
analysis. Logistic regression revealed several risk factors such as
elder age, greater affected lobe numbers and higher level of serum CRP
for the mortality of severe COVID-19 patients. Longitudinal changes of
laboratory findings indicate the advancement of the disease and may be
helpful in predicting the progression of severe patients.