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Maternal and perinatal Health Research Collaboration, India (MaatHRI): establishing a hospital-based international collaborative research platform
  • +25
  • Manisha Nair,
  • Babul Bezbaruah,
  • Amrit Bora,
  • Krishnaram Bora,
  • Shakuntala Chhabra,
  • Saswati Choudhury ,
  • Arup Choudhury,
  • Dipika Deka,
  • Gitanjali Deka,
  • Vijay Anand Ismavel,
  • Swapna Kakoty,
  • Roshine Koshy,
  • Pramod Kumar,
  • Pranabika Mahanta,
  • Robin Medhi,
  • Pranoy Nath,
  • Anjali Rani,
  • Indrani Roy,
  • Usha Sarma,
  • Carolin Solomi,
  • Ratna Talukdar,
  • Farzana Zahir,
  • Michael Hill,
  • Nimmi Kansal,
  • Reena Nakra,
  • Colin Baigent,
  • Marian Knight,
  • Jennifer Kurinczuk
Manisha Nair
University of Oxford

Corresponding Author:[email protected]

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Babul Bezbaruah
Silchar Medical College and Hospital
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Amrit Bora
Mahendra Mohan Choudhury Hospital
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Krishnaram Bora
Nagaon Bhogeswari Phukanani Civil Hospital
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Shakuntala Chhabra
Mahatma Gandhi Institute of Medical Sciences
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Saswati Choudhury
Gauhati Medical College and Hospital
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Arup Choudhury
Dhubri Civil Hospital
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Dipika Deka
Srimanta Sankaradeva University of Health Sciences
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Gitanjali Deka
Tezpur Medical College
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Vijay Anand Ismavel
Makunda Christian Leprosy and General Hospital
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Swapna Kakoty
Fakhruddin Ali Ahmed Medical College and Hospital
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Roshine Koshy
Makunda Christian Leprosy and General Hospital
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Pramod Kumar
Mahatma Gandhi Institute of Medical Sciences
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Pranabika Mahanta
Jorhat Medical College and Hospital
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Robin Medhi
Fakhruddin Ali Ahmed Medical College and Hospital
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Pranoy Nath
Silchar Medical College and Hospital
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Anjali Rani
Banaras Hindu University Institute of Medical Sciences
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Indrani Roy
Nazareth Hospital
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Usha Sarma
Tezpur Medical College
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Carolin Solomi
Makunda Christian Leprosy and General Hospital
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Ratna Talukdar
Gauhati Medical College and Hospital
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Farzana Zahir
Assam Medical College and Hospital
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Michael Hill
University of Oxford
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Nimmi Kansal
Dr Lal PathLabs
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Reena Nakra
Dr Lal PathLabs
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Colin Baigent
University of Oxford
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Marian Knight
National Perinatal Epidemiology Unit
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Jennifer Kurinczuk
University of Oxford
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Abstract

Objective: To describe the processes used to establish and standardise a UK-India collaborative platform for maternal and perinatal health research (MaatHRI). Design: Hospital-based research platform. Setting: India Population: Pregnant women Methods: MaatHRI is adapted from the UK Obstetric Surveillance System (UKOSS) and built on a pilot model (IndOSS-Assam), which has been extensively standardised using the following methods: (i) establishing a network of hospitals; (ii) setting up a secure system for data collection, storage and transfer; (iii) developing a standardised laboratory infrastructure; and (iv) developing and implementing regulatory systems. Results: MaatHRI was established in September 2018. Fourteen hospitals participate across four states in India – Assam, Meghalaya, Uttar Pradesh and Maharashtra. The Indian research team includes 20 nurses, a project manager, 16 obstetricians, two pathologists, a public health specialist, a general physician and a paediatrician. The UK partners include clinicians and epidemiologists from the University of Oxford. MaatHRI has advanced standardisation of data and laboratory parameters, monitoring data and participant safety, and secure transfer of data. An integral component of MaatHRI is bi-directional capacity building. It is overseen by a steering committee and a data safety and monitoring board which ensure equitable partnerships between the collaborating institutions. Conclusion: MaatHRI is the first prototype of UKOSS and other similar platforms in a low and middle income country (LMIC). The model used to develop the platform can be replicated in other LMICs. Funding: Medical Research Council Career Development Award to Manisha Nair (Ref:MR/P022030/1).