Pancreas tissue concentration and pharmacokinetics analysis of
vancomycin for severe acute pancreatitis: a case report
Abstract
Antibiotic concentration in pancreas tissue is very important for the
treatment of severe acute pancreatitis (SAP) with infection. We report a
case of a 44-year-old female with SAP on treatment of vancomycin. The
time courses of vancomycin concentration in serum and pancreas tissue of
the patient was described. This case demonstrated that it took about 30
minutes for vancomycin to get through from serum to pancreas tissue and
about 76% of vancomycin could move into pancreas tissue for SAP
patients.