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First whole genome sequences and phylogenetic analysis of SARS-CoV-2 virus isolates during COVID-19 outbreak in Tunisia, North Africa.
  • +17
  • wasfi fares,
  • Anissa Chouikha,
  • Kais Ghedira,
  • Mariem Gdoura,
  • Dorra Rezig,
  • Sondes Haddad Boubaker,
  • Imene Ben Dhifallah,
  • Henda Touzi,
  • Walid Hammami,
  • ZIna Meddeb,
  • Amel Sedraoui,
  • Nahed Hogga,
  • Imen Abouda,
  • Aurelia Kwasiborski,
  • Veronique Hourdel,
  • Guillain Mikaty,
  • Valerie Caro,
  • Jean-Claude Manuguerra,
  • Nissaf Ben Alaya,
  • Henda Triki
wasfi fares
Institut Pasteur, University Tunis-El Manar, Tunis, Tunisia

Corresponding Author:[email protected]

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Anissa Chouikha
Institut Pasteur, University Tunis-El Manar, Tunis, Tunisia
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Kais Ghedira
Institut Pasteur, University Tunis-El Manar, Tunis, Tunisia
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Mariem Gdoura
Institut Pasteur, University Tunis-El Manar, Tunis, Tunisia
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Dorra Rezig
Institut Pasteur, University Tunis-El Manar, Tunis, Tunisia
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Sondes Haddad Boubaker
Institut Pasteur, University Tunis-El Manar, Tunis, Tunisia
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Imene Ben Dhifallah
Institut Pasteur, University Tunis-El Manar, Tunis, Tunisia.
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Henda Touzi
Institut Pasteur, University Tunis-El Manar, Tunis, Tunisia.
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Walid Hammami
Institut Pasteur, University Tunis-El Manar, Tunis, Tunisia.
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ZIna Meddeb
Institut Pasteur, University Tunis-El Manar, Tunis, Tunisia.
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Amel Sedraoui
Institut Pasteur, University Tunis-El Manar, Tunis, Tunisia
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Nahed Hogga
Institut Pasteur, University Tunis-El Manar, Tunis, Tunisia
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Imen Abouda
Institut Pasteur, University Tunis-El Manar, Tunis, Tunisia
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Aurelia Kwasiborski
Institut Pasteur, Paris, France
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Veronique Hourdel
Institut Pasteur, Paris, France
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Guillain Mikaty
Institut Pasteur, Paris, France
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Valerie Caro
Institut Pasteur, Institut Pasteur, Paris, France
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Jean-Claude Manuguerra
Institut Pasteur, Paris, France
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Nissaf Ben Alaya
Tunisian Ministry of Health
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Henda Triki
Institut Pasteur, University Tunis-El Manar, Tunis, Tunisia
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Abstract

Full genomes sequences of six Tunisian SARS-CoV-2 strains were obtained from imported and locally transmission cases during the COVID-19 outbreak. Reported sequences were non-identical with 0.1% nucleotide divergence rate and clustered into 6 different clades with worldwide sequences. SNPs results favor the distribution of the reported Tunisian sequences into 3 major genotypes. These results indicate multiple introductions of the virus in Tunisia and add new genomic data on SARS-CoV-2 at the international level.