BACTEREMIA BY CARBAPENEMASE PRODUCING ENTEROBACTERIACEAE CAN BE REDUCED
BY MEASURES OF HOSPITAL INFECTION CONTROL
Abstract
Carbapenemase-producing Enterobacteriaceae (CPE) , multidrug resistant
(MDR) threatens children undergoing chemotherapy. A previous survey
reported increase of bloodstream infections and colonization in a 2
year-observation time. To test the efficacy of the measures put in place
, a second survey was performed. Data were collected from 13 Italian
pediatric cancer centers of AIEOP network. The colonization rate per
1000 hospitalizations days was 0.5 (0.37-0.65) not different from the
0.48 rate (0.36-0.63) observed previously .Yet the 0.12 rate of
bacteriemia (0.07-0.21) compared favorably with the 0.42 (0.31-0.57)
observed. The awareness of colonization status allowed reducing CPE
related morbidity and mortality.