EFFECTIVENESS OF UTERINE TAMPONADE DEVICES FOR REFRACTORY POSTPARTUM
HAEMORRHAGE AFTER VAGINAL BIRTH: A SYSTEMATIC REVIEW
Abstract
Objectives: to evaluate the effectiveness of uterine tamponade devices
for atonic refractory postpartum haemorrhage (PPH) after vaginal birth,
and the effect of including uterine tamponade devices in institutional
protocols. Search strategy: databases in PubMed, EMBASE, CINAHL, LILACS
and POPLINE. Study selection: randomised and non-randomised comparative
studies. Outcomes: composite outcome including surgical interventions
(artery ligations, uterine compressive sutures or hysterectomy) or
maternal death, and hysterectomy. Results: all four included studies
were at high risk of bias. The certainty of evidence rated as very low
to low. One randomised study measured the effect of the the
condom-catheter balloon compared to standard care and found unclear
results for the composite outcome (RR 2.33, 95%CI 0.76-7.14) and
hysterectomy (RR 4.14, 95%CI 0.48-35.93). Three comparative studies
assessed the effect of including UBTs in institutional protocols. A
stepped-wedge study suggested an increase in the composite outcome (RR
4.08, 95%CI 1.07-15.58), and unclear results for hysterectomy (RR 4.38,
95% CI 0.47-41.09) with the use of the condom-catheter or surgical
glove balloon. One non-randomised study showed unclear effects on the
composite outcome (RR 0.33, 95%CI 0.11-1.03) and hysterectomy (RR 0.49,
95%CI 0.04-5.38) after the inclusion of Bakri balloon. The second
non-randomized study found unclear effects on the composite outcome (RR
0.95, 95%CI 0.32-2.81) and hysterectomy (RR 1.84, 95%CI 0.44-7.69)
after the inclusion of Ebb or Bakri balloon. Conclusions: the effect of
uterine tamponade devices for the management of atonic refractory PPH
after vaginal delivery is unclear, as is the role of the type of device
and the setting.