Left ventricular and atrial global strain evaluation within subtypes of
ventricular remodeling
Abstract
Background: Left ventricular hypertrophy is associated with poor
prognosis and ad-verse events. Left ventricular and left atrial global
strain and left atrial reservoir strain (LV-GS; LA-GS; LA-RS) could be
used as markers for myocardial function in different forms of
ventricular remodeling. The aim of this study was to evaluate LV-GS and
LA-GS scores in different ventricular remodeling variants and identify
risk factors for myo-cardial dysfunction. Methods and Results: This
cross-sectional study was divided into four groups of ventricular
remodeling: normal geometry, eccentric hypertrophy (EH), concentric
hypertrophy (CH) and concentric remodeling (CR). Strain analysis was
obtained using standardized protocols. We included 121 subjects, 33 with
previous myocardial infarction (MI). We found that EH had the lowest
LV-GS and CH the lowest LA-GS and LA-RS. Atrial and ventricular
dysfunction was present in 40 (33%) and 14 (11.5%) subjects,
respectively. Smoking, male sex and previous MI were associated with LV
dysfunction and smoking and dyslipidemia with LA dysfunction. EH was
closely associated with LV dysfunction and CH with LA dysfunction.
Conclusions: We conclude that different types of ventricular geometry
had echocardiographic profiles associated with different risk factors
for dysfunction assessed by strain. The assessment of ventricular
remodeling by global strain could be used as a complementary tool in the
echocardiographic evaluation of ventricular and atrial function.