Systemic ALK-positive anaplastic large cell lymphoma with bilateral optic neurolymphomatosis resulting in permanent blindness

Karan Seegobin; Muhamad Alhaj Moustafa; Deborah Fischer; Katelyn Keller; Jacquelyn Hastings; Mohamed Kharfan Dabaja; Ernesto Ayala; Han W. Tun; Liuyan Jiang

doi:10.22541/au.159414342.27789314

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Systemic ALK-positive anaplastic large cell lymphoma with bilateral optic neurolymphomatosis resulting in permanent blindness

Karan Seegobin,
Muhamad Alhaj Moustafa,
Deborah Fischer,
Katelyn Keller,
Jacquelyn Hastings,
Mohamed Kharfan Dabaja ,
Ernesto Ayala,
Han W. Tun,
Liuyan Jiang

Abstract

A 26-year-old female developed bilateral blindness after a complete remission for ALK-positive ALCL. Initial workup showed neurolymphomatosis involving the bilateral optic nerves. She underwent hematopoietic cell transplantation and she remained in complete remission after 1 year; however her vision never improved. ALCL likely led to destruction of the optic pathway.

01 Jul 2020Submitted to Clinical Case Reports

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04 Jul 2020Submission Checks Completed

04 Jul 2020Assigned to Editor

15 Jul 2020Review(s) Completed, Editorial Evaluation Pending

20 Jul 2020Editorial Decision: Accept

14 Aug 2020Published in Clinical Case Reports. 10.1002/ccr3.3231

Abstract

Peer review status:Published