As of 16 July 2020, globally about 13.4 million cases of coronavirus disease 2019 (COVID-19) have been confirmed with nearly 600000 deaths. One of the main concerns about COVID-19 is long-term complications. Viruses account for about one-fifth of human cancer cases [1, 2]. Herein, three possible mechanisms of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as an oncogenic virus in the lung have been discussed briefly.