Abstract
Coronavirus disease of 2019 (COVID-19) is a public health emergency of
international concern caused by a novel coronavirus, i.e., Severe Acute
Respiratory Syndrome Coronavirus -2 (SARS-CoV-2). Since it is a new
virus, an effective remedy against the virus is yet unknown. SARS-CoV-2
is a member of order nidovirales, family coronaviridae. Previously known
treatment strategies against Middle East Respiratory Syndrome and Severe
Acute Respiratory Syndromes are being tested for their effectiveness
against SARS-CoV-2. Thus, various clinical and observational studies
aimed at identifying potential therapies against the disease. In our
study, we reviewed various drugs along with their mechanism of action
including anti-virals, anti-bacterials, glucocorticoids, ACE inhibitors,
anti retrovirals, anti-malarials, monoclonal antibodies, plasma and many
more. Individual drugs are described and evaluated for their potential
to treat SARS-CoV-2 infection. This study offers a brief review of the
findings of trials conducted so far. Dexamethasone, convalescent plasma
therapy, tocilizumab, remdesivir and combination therapies are found to
be beneficial against SARS-CoV-2.