Abstract The novel of coronavirus disease 2019 (COVID-19), originating in Wuhan, China, has become a major public health challenge for not only China but also countries around the world. The World Health Organization announced that the outbreaks of the novel coronavirus have constituted a public health emergency of international concern. As of February 26, 2020, COVID-19 has been recognized in 34 countries include many of the Gulf countries notably Iran and all other Gulf countries have reported COVID-19 cases respectively, the infectious gradually became serious, with a higher laboratory-confirmed cases and more deaths around the world. In this manuscript, we are going to try to elucidate shortly the infectious pandemic significantly in all Gulf countries and additionally investigate the competition between various of ABO blood groups which one is more susceptible than others and high risk for others with the second diseases. The effective infection control protocols are urgently needed around the world. This article, based on our experience and relevant guidelines and research to collect and introduces essential knowledge about COVID-19 as well as prevention and treatment are the most important task in the Gulf states