Preeclampsia and Its Complications Exacerbate Development of Postpartum
Depression: A Retrospective Cohort Study
Abstract
Objective: We aimed to determine the incidence rate of PPD in PE
patients and comprehensively evaluate the association between PPD and
PE, including its severity and complications. Design: A retrospective
cohort study. Setting: Two cities in China (Chongqing & Xining).
Population: 425 pregnant women. Methods: Totally 425 participants
including 130 PE mothers were enrolled in this study. Each woman was
asked to complete a questionnaire within 6 weeks after delivery,
integrating Edinburgh Postnatal Depression Scale (EPDS), Leakage Index
Questionnaire, and a pain-scale questionnaire. Main Outcome Measures:
The positive screening of postpartum depression between PE and normal
pregnant population. Results: The positive rate for PPD in PE group was
significantly higher than the control group (30.77% vs. 14.58%). Based
on the results of the regression model, women diagnosed with severe PE
and FGR were more inclined to develop PPD than normal ones. Postpartum
pain tend to exacerbate the odds of PPD among PE patients. Conclusions:
PE was an independent risk factor for PPD. Its severity and
complications exacerbate the development of PPD. Families and society
should pay more attentions on PE patients after delivery to against the
development of PPD.