Hand Sewn Bovine Pericardial Conduit with Tri-leaflet Valve in Right
Ventricular Outflow Tract: Review of 41 patients.
Abstract
Introduction: The currently available options for restoring right
ventricle (RV) to pulmonary artery (PA) continuity are far from
satisfactory. In absence of an ideal conduit, hand sewn bovine
pericardial conduit with Polytetrafluroethylene (PTFE) tri-leaflet valve
(BPCTV) may serve as a satisfactory alternative particularly in low and
middle income countries (LMIC). Material and Methods: The hospital
records of all patients who received BPCTV in RV to PA position from
January 2014 to June 2019 were retrospectively analysed. A total of 41
patients were further classified into two groups; pulmonary hypertension
group (PH) and non-pulmonary hypertension group (NPH). The primary
endpoints of the study were mortality, and freedom from re-operation for
conduit failure. The secondary end point was to study the impact of
pulmonary hypertension on the conduit function and durability. Results:
The Mean age and weight of patients at time of conduit implantation was
56.8 months (range 2-196 months) and 12.3 kg (range 3-44 kg)
respectively. The mean size of conduit was 18 mm (range 12-24 mm). The
mean duration of follow up was 30 months (range 8-72 months). The
freedom from re-intervention was 86% at 30 months (range 8-72 months).
The cost of BPCTV was less than one-sixth of the commercially available
bovine jugular vein conduit. Conclusion: The hand sewn BPCTV is a cost
effective alternative to commercially available conduits with acceptable
outcomes. However, more research with a larger sample size and a longer
follow-up is required.