In COVID-19 pneumonia, high-sensitive troponin I independently related
with tricuspid regurgitation pressure gradient
Abstract
Background: We aimed to determine the clinical, laboratory and
echocardiographic parameters associated with an increased
high-sensitivity cTnI (hs-cTnI) levels in COVID-19 pneumonia who
admitted to the emergency department. Methods: This cross-sectional
study included 70 COVID-19 patients with and without pneumonia. In
addition to medical history, physical examination and laboratory tests,
echocardiography and lung computed tomography was performed. The hs-cTnI
value of the patients’ ≥14ng/L for men and ≥18ng/L for women was
considered as an increased hs-cTnI. The patients were compared in two
groups, with and without pneumonia. Results: Tricuspid regurgitation
pressure gradient (TRPG) were higher in patients with COVID-19 pneumonia
(p<0.05). Tricuspid annular plane systolic excursion (TAPSE)
were lower in patients with COVID-19 pneumonia (p<0.05). In
regression analysis; HR, NT-proBNP and TRPG was found to be related to
hs-cTnI (p<0.01). Discussion: The most important determinants
of increased hs-cTnI level in these patients are; increased NT-proBNP
and TRPG. Therefore, it is necessary to follow-up the RV functions and
TRPG by echocardiography in patients with increased hs-cTnI and COVID-19
pneumonia.