Title: Comment on: A pilot study of ruxolitinib as a front-line therapy for 12 children with secondary hemophagocytic lymphohistiocytosisAuthors: Huan Xu1, Hongbo Chen1Affiliations: 1 Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaCorrespondence: Hongbo Chen, Address: Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Wuhan 430022, China, Telephone: +86-13006114930, Email: [email protected] Count for Main Text: 505Running Heads： Ruxolitinib therapy for HLH in childrenKeywords: Ruxolitinib, HLH, therapy