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Clinical efficacy of dupilumab in the treatment of severe chronic rhinosinusitis
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  • Matteo Trimarchi,
  • Pietro Indelicato,
  • Alessandro Vinciguerra,
  • Mario Bussi
Matteo Trimarchi

Corresponding Author:[email protected]

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Pietro Indelicato
San Raffaele Hospital
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Alessandro Vinciguerra
San Raffaele Hospital
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Mario Bussi
San Raffaele Hospital
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Abstract

Chronic rhinosinusitis with nasal polyps is a type 2-mediated inflammatory disease associated with significant burden due to symptoms and high recurrence rate after surgery. Dupilumab, a monoclonal antibody against the interleukin-4 receptor subunit α, has demonstrated good clinical efficacy and acceptable safety in phase II and phase III trials.

Peer review status:ACCEPTED

18 Nov 2020Submitted to Clinical Case Reports
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02 Dec 2020Submission Checks Completed
02 Dec 2020Assigned to Editor
08 Dec 2020Reviewer(s) Assigned
10 Dec 2020Review(s) Completed, Editorial Evaluation Pending
19 Dec 2020Editorial Decision: Revise Minor
22 Dec 20201st Revision Received
23 Dec 2020Submission Checks Completed
23 Dec 2020Assigned to Editor
23 Dec 2020Review(s) Completed, Editorial Evaluation Pending
28 Dec 2020Editorial Decision: Accept