Comparison of endoscopic and microscopic management of attic
cholesteatoma: A randomized controlled trial
Abstract
Objectives: To compare the endoscopic approach to manage attic
cholesteatoma with conventional microscopic technique. Design:
Randomized controlled trial. Participants: A total of 190 patients (192
ears) diagnosed with attic cholesteatoma extending to the antrum area
(stages Ib and II) were randomly assigned into two groups: one
undergoing endoscopic approach and the other undergoing the microscopic
technique. Main outcome measures: The two groups were compared in terms
of preoperative and intraoperative findings, access to hidden areas
expressed in terms of the Middle Ear Structural Visibility Index
(MESVI), mean operative time, and postoperative findings. Results: No
difference in the parameters of the preoperative and intraoperative
findings analyzed (patient age, computed tomography findings, disease
stage, and intraoperative cholesteatoma characteristics) was observed
between the endoscopic and microscopic groups. The median MESVI for the
endoscopic group was better than that for the microscopic group
(P<0.05). The mean operating time using the endoscopic
approach was less than that using the microscopic approach
(P<0.05). The median postoperative pain score in the
endoscopic group was lower than that in the microscopic group
(P<0.05). No significant difference was found between the two
groups in terms of taste sensation, air-bone gap closure at the end of 4
weeks, and vertigo experienced at the end of the first week. When
long-term surgical outcomes were assessed 1 year postoperatively, five
patients in the microscopic group had recurrence, four had cartilage
displacement, three had perforation, and five had retraction pocket
formation. In the endoscopic group, four patients had disease
recurrence, three had cartilage displacement, two had perforation, and
four had retraction pocket formation. Conclusion: Endoscopic management
of limited attic cholesteatoma showed definite advantages over the
conventional microscopic approach, such as providing better
visualization, requiring less postoperative time, subjecting the
patients to less pain, and decreasing the incidence of complications.