Comparison of Stroke Cases with Other Neurological Diseases on the Basis
of Hemogram Parameters
Abstract
Background This study aimed to examine the hemogram parameters,
including the neutrophil/lymphocyte ratio (NLR), which is fast, easy and
practical to determine, in stroke patients who present with more
physiological stress and inflammation and compare them with patients
presenting other neurological diseases. Methods The demographic,
laboratory and imaging features of all patients who were admitted to the
Neurology Service within a three-year period and met the study criteria
were retrospectively analyzed. A hemogram from peripheral venous blood
samples was taken at the time of admission, and the NLR was calculated.
Results A total of 3,152 patients, 1,604 of whom were women (50.9%),
with a mean age of 66.1 ± 14 (18-100) years who were hospitalized in the
neurology clinic between January 1, 2015 and January 1, 2018, comprised
the study’s sample. Mean age, mean leukocyte-neutrophil count and NLR
were significantly higher in stroke patients than in those without
stroke (p <0.001, p <0.001 and p <0.001,
respectively), but mean red blood cell, platelet and lymphocyte counts,
and hemoglobin and hematocrit values were found to be significantly
lower (p <0.001, p <0.001, p <0.001, p
<0.001 and p<0.001 respectively). When the hemogram
parameters were compared according to stroke type, red blood cell,
hemoglobin, hematocrit and NLR values in patients with hemorrhagic
stroke (p = 0.019, p = 0.002, p = 0.002 and p = 0.001, respectively) and
platelet and lymphocyte values in ischemic stroke patients were found to
be significantly higher (p = 0.002 and p <0.001,
respectively). Conclusion In this study, significant data obtained by
comparing the hemogram parameters of those with stroke and other
neurological diseases are presented. All neurological diseases,
especially acute stroke and its types, should be examined in future
prospective, randomized and controlled studies with all hemogram
parameters, especially the NLR (low cost)