A 68-year-old female was operated for a giant dedifferentiated retroperitoneal liposarcoma (RLS) encasing entirely the right kidney. She had an en-bloc resection of the tumor with right nephrectomy. The en-bloc resection should avoid R1 resection margins. Renal conservation is suggested if the kidney is widely displaced and for elderly patient.

Tailgut cysts are rare diseases but require a particular management. We present two cases report of a tailgut cyst two females. treated with transabdominal surgical approach. We review the relevant information present in the medical literature about the incidence, methods of diagnosis, treatment options and management plans.