Primary herpetic oropharyngitis in adults: Differences in clinical
features between Herpes simplex virus type 1 and type 2. A retrospective
study.
Abstract
Key points 1. This is the first report of adult primary herpetic
oropharyngitis in the view point of the differences between the two
types of herpes simplex virus (HSV). 2. 41 (25 type 1 and 16 type 2) HSV
specific antigen positive cases among 68 immunoserologically confirmed
adult HSV primary infection cases were investigated. 3. Significantly
low incidence of oral lesions and high incidence of nausea were seen in
HSV type 2 oropharyngitis cases, that might mean particular correlation
vagus nerve and HSV type 2. 4. Significantly increased white blood cell
count and high C-reacative protein value were seen in oropharyngitis by
HSV type 2. 5. HSV type 2 possibly cause more severe symptoms and higher
inflammatory reactions than type 1, without oral lesions.