Essential Site Maintenance: Authorea-powered sites will be updated circa 15:00-17:00 Eastern on Tuesday 5 November.
There should be no interruption to normal services, but please contact us at [email protected] in case you face any issues.

loading page

SARS-CoV-2 Re-Infection versus Prolonged Shedding: A Case Series
  • +6
  • Erin Nicholson,
  • Vasanthi Avadhanula,
  • Sonia Fragoso,
  • Rachel Stroh,
  • Xunyan Ye,
  • Nanette Bond,
  • Patricia Santarcangelo,
  • John Stroh,
  • Pedro Piedra
Erin Nicholson
Baylor College of Medicine

Corresponding Author:[email protected]

Author Profile
Vasanthi Avadhanula
Baylor College of Medicine
Author Profile
Sonia Fragoso
Baylor College of Medicine
Author Profile
Rachel Stroh
Baylor College of Medicine
Author Profile
Xunyan Ye
Baylor College of Medicine
Author Profile
Nanette Bond
Baylor College of Medicine
Author Profile
Patricia Santarcangelo
Baylor College of Medicine
Author Profile
John Stroh
CHI St Luke's Health
Author Profile
Pedro Piedra
Baylor College of Medicine
Author Profile

Abstract

Since the start of the SARS-CoV-2 pandemic, it has been difficult to differentiate between SARS-CoV-2 re-infection and prolonged RNA shedding. In this report, we identified patients with positive rtPCR results for SARS-CoV-2 ≥70 days apart. Clinical and laboratory data were collected and criteria were applied to discern whether the presentation was consistent with SARS-CoV-2 re-infection or prolonged viral RNA shedding. Eleven individuals met the initial testing criteria, of which, seven met at least one criteria for re-infection and four were consistent with prolonged RNA shedding. These data demonstrate the need for criteria to differentiate SARS-CoV-2 re-infection from prolonged RNA shedding.
30 Apr 2021Submitted to Influenza and other respiratory viruses
03 May 2021Submission Checks Completed
03 May 2021Assigned to Editor
16 May 2021Editorial Decision: Accept
Nov 2021Published in Influenza and Other Respiratory Viruses volume 15 issue 6 on pages 691-696. 10.1111/irv.12879