Hydatid cyst of pulmonary artery is extremely rare. There were few reports of intramural involvement of pulmonary artery secondary to cardiac or lung hydatic cyst in literature. To the best of our knowledge there was no report of primary isolated extraluminal hydatid cyst of left pulmonary artery. A twenty-eight–year-old female presented to the hospital with complaint of progressive dyspnea. The patients had no common COVID-19 infection symptoms. The RT-PCR for COVID-19 RNA was negative. Spiral chest CT-scan demonstrated a cystic mass sized 83×34 in middle mediastinum. Intraoperatively, the intrapericardial mass arising from left pulmonary artery and extended to the hilum of left atrium. The mass was resected and pathology report noted a hydatid cyst. The postoperative course was uneventful and the patient was discharged with administration of albendazol for 3 months. However hydatid cyst primary isolated extraluminal hydatid cyst of pulmonary artery are extremely rare, in cases with pulmonary artery stenos or hypertension manifestation should be considered as a probable differential diagnoses. Regarding to ongoing COVID-19 pandemic the present case misdiagnosed with coronavirus infection.