Renal involvement in spondyloarthritis is dominated by amyloidosis, IgA nephropathy and urolithiasis. Other nephropathies are rare . A patient followed for SpA consults with edema , hydrocele and a pleural effusion. A FSGS was confirmed by renal biopsy and the etiological investigation has ruled out the causes of secondary FSGS.

Granulomatosis reaction associated with tumor has been designated as sarcoid-like reaction. Very few cases of association of systemic sarcoidosis and neoplasia have been reported. We reported two cases of sarcoidosis and renal cell carcinoma.