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Improvement of Depression in a Patient with Hypothyroidism and Deiodinase Polymorphism with LT3 Therapy
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  • Ziyan Ahmed,
  • Rinsha Sherin,
  • Thanh Hoang,
  • Tatiana Fonseca,
  • Mohamed Shakir
Ziyan Ahmed
Walter Reed National Military Medical Center

Corresponding Author:[email protected]

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Rinsha Sherin
Walter Reed National Military Medical Center
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Thanh Hoang
Walter Reed National Military Medical Center
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Tatiana Fonseca
University of Chicago Andy Minn Oncology Lab
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Mohamed Shakir
Walter Reed National Military Medical Center
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Abstract

We report a 54-year-old man with treatment-resistant depression (TRD) and hypothyroidism who responded to LT3/LT4 combination, rather than LT4 alone. He was able to discontinue all antidepressant medications eventually. Interestingly, the patient has a DIO2 polymorphism.

Peer review status:Published

31 Aug 2021Submitted to Clinical Case Reports
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01 Sep 2021Submission Checks Completed
01 Sep 2021Assigned to Editor
24 Sep 2021Reviewer(s) Assigned
19 Oct 2021Review(s) Completed, Editorial Evaluation Pending
06 Nov 2021Editorial Decision: Revise Minor
22 Nov 20211st Revision Received
22 Nov 2021Assigned to Editor
22 Nov 2021Submission Checks Completed
22 Nov 2021Review(s) Completed, Editorial Evaluation Pending
13 Dec 2021Reviewer(s) Assigned
01 Jan 2022Editorial Decision: Revise Minor
30 Jan 20222nd Revision Received
31 Jan 2022Submission Checks Completed
31 Jan 2022Assigned to Editor
31 Jan 2022Review(s) Completed, Editorial Evaluation Pending
13 Feb 2022Reviewer(s) Assigned
07 Mar 2022Editorial Decision: Accept
Apr 2022Published in Clinical Case Reports volume 10 issue 4. 10.1002/ccr3.5651