A 22-year-old male presented with chest pain 3 days after his second dose of the COVID-19 vaccine. Cardiac magnetic resonance imaging demonstrated myocardial and pericardial enhancement. Given imaging and clinical findings, he was diagnosed with perimyocarditis. He was treated with a multitude of medications including NSAIDs, colchicine, and steroids. Fortunately, he was able to achieve symptom improvement. Due to COVID-19 vaccination novelty, further research is needed to identify side effects.