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Severe pancytopenia caused by trifluridine/tipiracil in patients with metastatic colorectal cancer and an impaired renal function: A case report
  • +6
  • Masatsune Shibutani,
  • Yuki Okazaki,
  • Shinichiro Kashiwagi,
  • Hisashi Nagahara,
  • Tatsunari Fukuoka,
  • Yasuhito Iseki,
  • Kiyoshi Maeda,
  • kosei Hirakawa,
  • Masaichi Ohira
Masatsune Shibutani
Osaka City University Graduate School of Medicine School of Medicine

Corresponding Author:[email protected]

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Yuki Okazaki
Osaka City University Graduate School of Medicine School of Medicine
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Shinichiro Kashiwagi
Osaka City University Graduate School of Medicine School of Medicine
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Hisashi Nagahara
Osaka City University Graduate School of Medicine School of Medicine
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Tatsunari Fukuoka
Osaka City University Graduate School of Medicine School of Medicine
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Yasuhito Iseki
Osaka City University Graduate School of Medicine School of Medicine
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Kiyoshi Maeda
Osaka City General Hospital
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kosei Hirakawa
Osaka City University Graduate School of Medicine School of Medicine
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Masaichi Ohira
Osaka City University Graduate School of Medicine School of Medicine
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Abstract

Although the incidence of hematological toxicity due to FTD/TPI treatment is high, the incidence of severe adverse events has been reported to be relatively low. However, it should be noted that patients with renal impairment are prone to severe hematological adverse events.
16 Sep 2021Submitted to Clinical Case Reports
01 Nov 2021Submission Checks Completed
01 Nov 2021Assigned to Editor
01 Nov 2021Reviewer(s) Assigned
27 Dec 2021Review(s) Completed, Editorial Evaluation Pending
27 Dec 2021Editorial Decision: Revise Minor
15 Jan 20221st Revision Received
17 Jan 2022Submission Checks Completed
17 Jan 2022Assigned to Editor
17 Jan 2022Review(s) Completed, Editorial Evaluation Pending
17 Jan 2022Reviewer(s) Assigned
16 Feb 2022Editorial Decision: Accept
Mar 2022Published in Clinical Case Reports volume 10 issue 3. 10.1002/ccr3.5544