Sentinel lymph node (SLN) refers to the initial site of the lymphatic drainage from a primary tumor area. Accordingly, sentinel lymph node mapping (SLNM) has been brought up and widely applied to cancer therapy for its illuminating role in clinical lymph node resection. Furthermore, sufficient information to guide surgical pathological staging and adjuvant treatment in endometrial cancer can be rendered by SLNM, hence minimizing surgery injury and reducing the incidence of complications. This review aims to systematically summarize the advances and application prospects of SLNM in endometrial cancer, with an expectation of furnishing reference for the clinical application.