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Fifteen-year experience with the Tirone David procedure in bicuspid aortic valve: a safe option.
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  • Charline PUJOS,
  • nicolas d'ostrevy,
  • Mehdi Farhat,
  • Etienne Geoffroy,
  • Nicolas Dauphin,
  • Adama SAWADOGO,
  • Celine Lambert,
  • Lionel Camilleri
Charline PUJOS
Centre Hospitalier Universitaire de Clermont-Ferrand

Corresponding Author:[email protected]

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nicolas d'ostrevy
Centre Hospitalier Universitaire de Clermont-Ferrand
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Mehdi Farhat
Centre Hospitalier Universitaire de Clermont-Ferrand
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Etienne Geoffroy
Centre Hospitalier Universitaire de Clermont-Ferrand
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Nicolas Dauphin
Centre Hospitalier Universitaire de Clermont-Ferrand
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Adama SAWADOGO
Centre Hospitalier Universitaire de Clermont-Ferrand
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Celine Lambert
Centre Hospitalier Universitaire de Clermont-Ferrand
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Lionel Camilleri
Centre Hospitalier Universitaire de Clermont-Ferrand
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Abstract

Background We evaluated short- and mid-term outcomes with use of aortic valve-sparing root replacement to treat bicuspid aortic valves. Methods From December 2007 to January 2022, all patients with bicuspid aortic valves who underwent aortic root replacement using Tirone’s procedure were included. This study based on department database information for retrospective and follow-up data. Results Among 51 adults undergoing aortic root replacement using Tirone’s procedure, the mean age was 47.4±12.5 years, and most were men (92.2%). Three presented with a dysmorphic syndrome and one had Marfan’s syndrome. All patients were alive at 30 days, and as of January 2022, 45 were alive, two were lost to follow-up, and there were four noncardiac deaths. Two patients had infectious endocarditis and needed a Bentall’s procedure. One patient had a double biologic valve replacement in the context of severe mitral insufficiency with moderate aortic stenosis at 4.5 years post-procedure. Echocardiographic follow-up showed a left ventricular ejection fraction of 63±7% (n=36), V max 2±0.6 m/s (n=17), and a mean gradient of 9.4±5.4 mmHg (n=27). No patients had grade 3 or 4 aortic regurgitation, one patient had grade 2, and four had grade 1. Conclusion Tirone’s procedure is an option for bicuspid aortic valve surgery, with good safety and outcomes, especially in younger patients.
07 Jun 2022Submitted to Journal of Cardiac Surgery
07 Jun 2022Submission Checks Completed
07 Jun 2022Assigned to Editor
09 Jun 2022Reviewer(s) Assigned
23 Jun 2022Review(s) Completed, Editorial Evaluation Pending
23 Jun 2022Editorial Decision: Revise Major
22 Jul 20221st Revision Received
22 Jul 2022Submission Checks Completed
22 Jul 2022Assigned to Editor
22 Jul 2022Reviewer(s) Assigned
30 Jul 2022Review(s) Completed, Editorial Evaluation Pending
30 Jul 2022Editorial Decision: Revise Minor
29 Aug 20222nd Revision Received
29 Aug 2022Submission Checks Completed
29 Aug 2022Assigned to Editor
30 Aug 2022Reviewer(s) Assigned
03 Sep 2022Review(s) Completed, Editorial Evaluation Pending
03 Sep 2022Editorial Decision: Accept
Nov 2022Published in Journal of Cardiac Surgery volume 37 issue 11 on pages 3469-3476. 10.1111/jocs.16953