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HOW WE APPROACH CONSERVATIVE TREATMENT OF RETINOBLASTOMA IN SOUTH AMERICA IN THE ERA OF LOCAL OCULAR TREATMENTS. A CONSENSUS OF THE GRUPO AMERICA LATINA DE ONCOLOGIA PEDIATRICA (GALOP)
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  • Juan López ,
  • Claudia Sampor,
  • Nathalia Grigorovski,
  • Alejandro Ceciliano,
  • Adriana Fandino,
  • Diego Ossandon,
  • Veronica Perez,
  • Rafaela Caixeta,
  • Joaquim Caetano de Aguirre Neto,
  • Sandra Alarcon,
  • Sónia Silva,
  • Luiz Teixeira,
  • Celia Antoneli,
  • Clarissa Matosinho,
  • Carlos Leal Leal,
  • Guilherme Castela,
  • Flavio Requejo,
  • Jaume Catala,
  • Carla Pacheco Donato Macedo,
  • Guillermo Chantada L
Juan López
Universidad de Chile Santiago Chile

Corresponding Author:[email protected]

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Claudia Sampor
Hospital de Pediatria Prof Dr Juan P Garrahan
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Nathalia Grigorovski
Instituto Nacional de Cancer
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Alejandro Ceciliano
Hospital Universitario Austral Pilar Argentina
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Adriana Fandino
Hospital de Pediatria Prof Dr Juan P Garrahan
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Diego Ossandon
Clinica Alemana de Santiago SA
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Veronica Perez
Hospital San Juan de Dios Santiago Chile
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Rafaela Caixeta
Hospital Santa Casa Belo Horizonte Brazil
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Joaquim Caetano de Aguirre Neto
Hospital Santa Casa Belo Horizonte Brazil
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Sandra Alarcon
Instituto Nacional de Enfermedades Neoplasicas
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Sónia Silva
Centro Hospitalar e Universitario de Coimbra EPE
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Luiz Teixeira
Universidade Federal de Sao Paulo Escola Paulista de Medicina Sao Paulo Brazil
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Celia Antoneli
Universidade Nove de Julho Sao Paulo Brazil
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Clarissa Matosinho
Instituto Nacional de Cancer
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Carlos Leal Leal
Hospital Infantil Privado Mexico City Mexico
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Guilherme Castela
Centro Hospitalar e Universitario de Coimbra EPE
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Flavio Requejo
Hospital de Pediatria Prof Dr Juan P Garrahan
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Jaume Catala
Hospital Sant Joan de Deu
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Carla Pacheco Donato Macedo
Universidade Nove de Julho Sao Paulo Brazil
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Guillermo Chantada L
Hospital Universitario Austral Pilar Argentina
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Abstract

Local therapies replaced systemic chemotherapy for ocular preservation in retinoblastoma. In middle income countries, these techniques pose specific challenges mostly related to more advanced disease at diagnosis. The Grupo de America Latina de Oncologia Pediatrica (GALOP developed a consensus document for the management of conservative therapy for retinoblastoma. Intra-arterial chemotherapy (OAC) is the preferred therapy, except those with less advanced disease or age younger than 6 months. OAC allowed for the elimination of the use of external beam radiotherapy in our setting. Intravitreal chemotherapy is the preferred treatment for vitreous seeding. Enucleation is the treatment of choice for advanced eyes.
11 Jul 2022Submitted to Pediatric Blood & Cancer
11 Jul 2022Submission Checks Completed
11 Jul 2022Assigned to Editor
31 Jul 2022Reviewer(s) Assigned
03 Sep 2022Review(s) Completed, Editorial Evaluation Pending
19 Sep 2022Editorial Decision: Revise Major
29 Nov 2022Submission Checks Completed
29 Nov 2022Assigned to Editor
29 Nov 20221st Revision Received
29 Nov 2022Review(s) Completed, Editorial Evaluation Pending
10 Dec 2022Reviewer(s) Assigned
11 Jan 2023Editorial Decision: Revise Minor
02 Mar 2023Submission Checks Completed
02 Mar 2023Assigned to Editor
02 Mar 20232nd Revision Received
02 Mar 2023Review(s) Completed, Editorial Evaluation Pending
20 Mar 2023Editorial Decision: Accept