In this paper, we derive two regularity criteria of solutions to the nematic liquid crystal flows. More precisely, we prove the local smooth solution $(u, d)$ is regular if and only if one of the following two conditions is satisfied: (i) $\nabla_{h} u_{h}\in L^{\frac{2p}{2p-3}}(0,T; L^{p}(\mathbb{R}^{3})),\ \partial_{3} d\in L^{\frac{2q}{q-3}}(0,T; L^{q}(\mathbb{R}^{3})),\ \frac{3}{2}< p\leq\infty,\ 3< q\leq\infty$; and (ii) $\nabla_{h} u_{h}\in L^{q}(0,T; L^{p}(\mathbb{R}^{3})),\ \frac{3}{p}+\frac{2}{q}\leq 1, \ 3