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REAL-WORLD IMPLEMENTATION OF NORTH AMERICAN AND SIOP STRATEGIES FOR THE TREATMENT OF WILMS TUMOR IN URUGUAY
  • +9
  • Diana Vargas,
  • Luisa Chantada,
  • Bruno Cuturi,
  • Anaulina Silveira,
  • Ángeles Rodríguez,
  • Luján Guerrero,
  • Lucia Díaz,
  • Mariela Castiglioni,
  • Fabiana Morosini,
  • Carolina Pagés,
  • Elizabeth Simón,
  • Luis Castillo
Diana Vargas
Sindicato Medico del Uruguay

Corresponding Author:[email protected]

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Luisa Chantada
Universidad de Buenos Aires
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Bruno Cuturi
Sindicato Medico del Uruguay
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Anaulina Silveira
Sindicato Medico del Uruguay
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Ángeles Rodríguez
Sindicato Medico del Uruguay
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Luján Guerrero
Sindicato Medico del Uruguay
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Lucia Díaz
Sindicato Medico del Uruguay
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Mariela Castiglioni
Sindicato Medico del Uruguay
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Fabiana Morosini
Sindicato Medico del Uruguay
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Carolina Pagés
Sindicato Medico del Uruguay
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Elizabeth Simón
Sindicato Medico del Uruguay
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Luis Castillo
Sindicato Medico del Uruguay
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Abstract

We performed an audit from 1995 to 2020 of patients with Wilms tumor in a referral center in Uruguay. Treatment included North American (NA) strategies (n=23) up to 2004 followed by SIOP strategy (n=35) thereafter (stage I-II=28, III=7, IV=14 and V=9). Delay in local radiotherapy was noted (median of 21 days after surgery). There was no toxic or surgical death or abandonment. Five-year pOS was 0.72 and 0.92 for the NA and SIOP respectively. Results favored the SIOP strategy with no unexpected toxicities and high treatment compliance in both strategies. Timely implementation of radiotherapy was challenging.