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Successful treatment with ivabradine in a β-blocker refractory patient with acute decompensated HFrEF
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  • Tomoko Inoue,
  • Keiji Matsunaga,
  • Waki Kobayashi,
  • Tetsuo Minamino
Tomoko Inoue
Faculty of Medicine, Kagawa University

Corresponding Author:[email protected]

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Keiji Matsunaga
Faculty of Medicine, Kagawa University
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Waki Kobayashi
Faculty of Medicine, Kagawa University
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Tetsuo Minamino
Faculty of Medicine, Kagawa University
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Abstract

Ivabradine is an established treatment for chronic heart failure with reduced ejection fraction (HFrEF) but not for acute heart failure. β-blocker up-titration is often not possible because of its negative inotropic effect (NIE). Ivabradine has no NIE; therefore, it may be preferred over β-blockers in patients with acute decompensated HFrEF.
14 Sep 2022Submitted to Clinical Case Reports
15 Sep 2022Submission Checks Completed
15 Sep 2022Assigned to Editor
17 Sep 2022Reviewer(s) Assigned
20 Oct 2022Review(s) Completed, Editorial Evaluation Pending
21 Oct 2022Editorial Decision: Revise Minor
28 Nov 20221st Revision Received
29 Nov 2022Submission Checks Completed
29 Nov 2022Assigned to Editor
29 Nov 2022Review(s) Completed, Editorial Evaluation Pending
29 Nov 2022Editorial Decision: Revise Minor
13 Dec 20222nd Revision Received
14 Dec 2022Submission Checks Completed
14 Dec 2022Assigned to Editor
14 Dec 2022Review(s) Completed, Editorial Evaluation Pending
03 Jan 2023Editorial Decision: Accept