Bullous pemphigoid is an autoimmune disorder characterized by blister formation. Hypereosinophilic syndrome is a myeloproliferative disorder that presents with papules, nodules, urticarial lesions, and blisters. The coexistence of these disorders may highlight common molecular and cellular factors. We describe a 16-years-old patient with coexistence of hypereosinophilic syndrome and bullous pemphigoid.