Hi Reddit, The company originates from a spin-off from NExT, a leading research centre jointly established between National University of Singapore (ranked 22nd in the world) and Tsinghua University of China (ranked 47th in the world). The spin-off happened in 2012 and since then we have secured series A funding and well-known customers like Flipkart, Rakuten, Zalora from Rocket Internet and more. Deep learning is a very hot area at the moment. There were lots of developments in the past years that made it progress, but as of now the main evolution will come from the way it is implemented for specific applications. Visual technologies like visual search and image recognition are some of these specialisations that require not only a great use of deep learning and computer vision but also good industry knowledge for the verticals where it is applied. There is a huge talent crunch in this space and we need more and more engineers to consider a career in machine intelligence, deep learning and computer vision. I am here to answer questions regarding the real-world applications for deep learning and computer vision and what it takes to develop algorithms and infrastructure architectures from a research centre all the way to a company with established customers. I can reveal the industry potential and latest challenges, as well as why and how someone can develop a career in this space. AMA! Read more about my company: https://visenze.com/ Explore live the product demo we have: https://visenze.com/demo

Hi Reddit, I am Yael Velleman, a Senior Policy Analyst for Health & Hygiene at WaterAid. My work focuses on the links between water, sanitation and hygiene and health, and the implications for policy and programs. I am Pinaki Panigrahi, a professor of Epidemiology, Pediatrics, and Environmental-Agricultural-and-Occupational Health at the University of Nebraska Medical Center, and also the Director of the Center for Global Health and Development at the College of Public Health at University of Nebraska. My current research focus is to study the impact of environmental exposures on maternal and child health. I am Oliver Cumming, a Lecturer in the Environmental Health in Department of Disease Control at the London School of Hygiene and Tropical Medicine. My research focuses on access to safe water, sanitation, and hygiene and its impacts on childhood health and development. We recently published papers in PLOS Medicine examining the impacts of water and sanitation programs on public health. In a paper titled “From Joint Thinking to Joint Action: A Call to Action on Improving Water, Sanitation, and Hygiene for Maternal and Newborn Health,” Yael and Oliver, in collaboration with several UN and academic agencies and institutions, set out the case for action on water, sanitation and hygiene for improving maternal and newborn health, and provided a set of policy recommendations. In “Risk of Adverse Pregnancy Outcomes among Women Practicing Poor Sanitation in Rural India: A Population-Based Prospective Cohort Study,” Pinaki and colleagues found that open defecation led to more adverse pregnancy outcomes. The study enrolled more than 600 pregnant women and researchers tracked their sanitation practice during pregnancy. Those practicing open defecation had higher number of bad pregnancy outcomes, especially preterm births. Many other concomitant factors were also studied (apart from defecation practice), and against conventional wisdom, we did not find socioeconomic status to play any role in this, but the pregnant woman’s education did. More research is needed to identify changes that are induced by open defecation ultimately driving an unhealthy pregnancy. We will be taking your questions about how WASH impacts global public health today at 1pm ET (10 am PT, 5 pm UTC) — Ask Us Anything! And don’t forget to follow Yael on Twitter at @YaelVelleman.

Welcome! I am M.G. Finn, Editor-in-Chief of ACS Combinatorial Science. My group does research in a variety of areas that seek to develop molecular function, but we define “molecular” in ways that go from small molecule drugs to large multiprotein assemblies to organisms. In particular, we develop and optimize reactions for bioconjugation and release, engineer virus-like nanoparticles for immunology, cell targeting, and enzyme encapsulation, and work on new ways to evolve aptamers and enzymes. Since moving to Georgia Tech in 2013, we are also doing a lot more materials science, trying to apply some of our click chemistry techniques and attitudes to the creation of new functional polymers and surfaces. An appreciation for molecular function is what motivated me to steer the journal into expanded waters, while retaining a core commitment to the publication of good synthetic chemistry. ACS Comb. Sci. now publishes papers in a wide variety of areas in which functional structures are made, identified, or enhanced by combinatorial means. We also like to highlight methods — synthetic, analytical, and theoretical — by which function can be created and measured. Combinatorial biology, materials development, and drug development are all combinatorial chemistry in my view, and so the field is most certainly very much alive. Thanks VERY much to everyone who posted questions and comments - I had a great time and you gave me some good things to think about. (Hopefully, that feeling is mutual.) I look forward to the next AMA.

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Hurricane Patricia is now one of the strongest recorded storms on the planet and is likely to make landfall as a Category 5 storm in Mexico on Friday evening. It’s a record-breaking meteorological marvel but could quickly turn into a major humanitarian crisis when it makes landfall. We’re two journalists and a meteorologist who work at WXshift, a Climate Central powered weather website that provides climate context for your daily forecast. We’re here to answer your questions about the records Patricia is setting, potential impacts and anything else you want to know about this storm or why this year has seen a record number of strong tropical cyclones in the northern hemisphere. Ask us anything! We are: Sean Sublette is an award-winning meteorologist at Climate Central and WXshift. He previously worked as the chief meteorologist at WSET in Lynchburg, Va. and currently hosts WXshift’s Shift Ahead Andrea Thompson is a senior science writer at Climate Central and WXshift who focuses on extreme weather and climate change. Brian Kahn is a senior science writer at Climate Central and WXshift. His recent coverage has included Patricia as well as the recent northern hemisphere hurricane record. EDIT: Thank you all for your really thoughtful questions. We’ll be continuing our coverage on the site as well as [Twitter](http://www.twitter.com/wxshift] so please follow along. And if you know anyone in the region, please tell them to be safe and seek shelter. This storm is serious.

EDIT: I’m now live - bring on your burning garbage questions, Reddit! Thanks for so many great questions so far, I’ll be hanging out Friday afternoon and checking up on new ones that arrive. Hi reddit, I, along with my co-authors, recently published a manuscript in Nature Climate Change that had a few key findings. First, we found that every American is disposing of about 5 pounds of waste per person per day, but that US landfills generally have several decades of life remaining. Second, we examined engineered systems built at landfills to collect gases produced when waste decomposes and identified the factors that most greatly impact the performance of these systems. Taken together, we identified areas where significant reductions in greenhouse gases can be achieved and uncovered opportunities for additional renewable energy production. I have worked on materials and waste management issues across multiple continents and am passionate about expanding the use of data to better understand how we manage materials in the US, with the goal of identifying hotspots where more sustainable decisions can be made. TL;DR America disposes of a lot of waste and we can reduce current/future gas emissions and produce more energy with improved gas collection practices.

Edit: We are live! Please continue to submit your questions. Hi Reddit, Our team of cardiologists at Henry Ford Hospital specializes in working with the sickest of the sick, offering pioneering options to patients with hard-to-treat advanced heart disease. One of our focuses has been on finding new, novel ways to access the heart. The Henry Ford team was the first to successfully perform transcatheter aortic valve replacement (TAVR) using a novel way to access the heart, called a transcaval access route. This is done through moving a catheter through a vein up into the body, then bridging in the patient’s abdomen into the aorta. I have had the pleasure of teaching this procedure to colleagues around the world, and the procedure has now been done in more than 125 patients at 18 centers throughout the world (16 in the U.S.). The Center for Structural Heart Disease cardiologists developed this procedure working closely with doctors at the National Heart, Lung and Blood Institute. We’re now sharing this technique with others in an effort to save lives. The transcaval procedure is particularly effective in patients whose arteries are too small for traditional transcatheter routes to the heart, where scarring from previous procedures makes access difficult, or where multiple procedures require elaborate access. It has been very gratifying to say to our advanced heart disease patients and their families, “We have another option,” when they’ve been told no option exists. EDIT: Thank you for tuning in! I’d be happy to speak with your doctor if you think this procedure might be a benefit to you or a loved one. For more information on our heart program: www.henryford.com/heart. Proof: https://twitter.com/HenryFordNews/status/657236352333946880?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Etweet Read more about transcaval heart procedure, here: http://www.henryford.com/body.cfm?id=46335&action=detail&ref=1943 https://www.henryford.com/body.cfm?id=60737 http://www.henryford.com/body.cfm?id=46335&action=detail&ref=2068 I also helped perform the first successful transcaval heart procedure in Europe. http://www.henryford.com/body.cfm?id=46335&action=detail&ref=2166

Hi Reddit! I am Lisa Balbes, a long-time Technical Writer/Editor and a volunteer Career Consultant with the American Chemical Society. I am here to discuss chemistry careers, nontraditional careers for scientists, and making career transitions. To give you a little background, I earned my Ph.D. in organic chemistry from the University of North Carolina at Chapel Hill, and my undergraduate degrees in chemistry and psychology from Washington University in St Louis. I spent several years as a computational chemist at Research Triangle Institute. For the past 23+ years, I have been running my own business, providing technical writing and editing services for organizations including Washington University Medical School, Bausch and Lomb Surgical, SigmaAldrich, Stereotaxis, and the US FDA. I addtion to my professional experience, I have been an American Chemical Society volunteer career consultant since 1993, providing career management advice and information to literally thousands of scientists worldwide. I am the author of “Nontraditional Careers for Chemists: New Formulas in Chemistry”, published by Oxford University Press in 2007. In 2012, I received the E. Ann Nalley Award for Outstanding Volunteer Service for the ACS Midwest Region, and in 2015 I received the Howard and Sally Peters Award from the ACS Division of Chemistry and the Law. I also volunteer with the Boy Scouts of America on both the Greater St Louis area Boy Scout STEM Committee and the national STEM/Nova committee. In 2015, I was the staff advisor for a week-long STEM Trek for Venturers at the Summit Bechtel Reserve in West Virginia, and have taught chemistry to thousands of youth in a tent on top of a mountain. I love sharing the world of science with youth, and opening their eyes to the possibilities. The ACS Career Consultant Program, an ACS member benefit, gives members access to a consultant to help guide you through job searching, career transitions, resume writing, and more. Take a look at this video I was featured in to learn more about the program. I have long felt that chemistry background prepares you for much more than just a laboratory career. The broad science education, analytical thinking, research methods, and other skills learned are of value to a wide variety of employers, and essential for a plethora of types of positions. By understanding both yourself and the employment market, you can make informed decisions about potential careers, and identify paths that match your needs. Possible career paths include chemical information, patent work, technical writing, education, human resources, sales, marketing, and much more. Knowing what you are good at, what you enjoy, and how to turn that into a career, is essential for success in today’s world. I’ll be back to answer questions at 1:00 PM ET (10 am PT, 5 pm UTC). Feel free to ask me anything about chemistry careers, nontraditional careers, and making career transitions. EDIT 1:00 PM: I’m here! Looks like I have lots to read, and I will start typing answers. Looking forward to some fun discussion! EDIT 2:06 PM: Wow, that went fast. Thanks for all the great questions! For more information about the ACS Career Consultants program, please visit http://www.acs.org/content/acs/en/careers/career-services/ccp.html Best of luck in your career endeavors!

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Happy Breast Cancer Awareness Month. A cancer is described as metastatic when cells break off from a primary tumor and spread to other parts of the body. For example, if breast cancer cells travel to the lungs and form a tumor there, that is a metastasis, or a metastatic breast cancer tumor, not lung cancer. Even one cancerous cell can break off a tumor, travel through the bloodstream and lodge itself in new tissue. Metastatic cells can start growing into tumors of their own right away, but often lie dormant for days, weeks, or even decades, only to flare up long after the primary tumor has been removed. Metastases cause the vast majority of cancer deaths, particularly in the case of breast cancer, where the original tumor is rarely deadly on its own. But the process by which cancer cells escape a primary tumor, invade other parts of the body, and seed new cancerous growths is poorly understood. In breast cancer in particular, we suspect that metastases are influenced by the intrinsically stem-cell-like genetic programs needed for breast tissue to grow during puberty and pregnancy. Only a small fraction of cancer research funding goes towards understanding metastases, partly because these tiny rogue cells are hard to find and study. As a result, deadly metastatic cancers are still extremely difficult to treat. Most cancer drugs are developed to shrink primary tumors, and they often don’t perform as well on metastatic tumors. My lab at UCSF is trying to uncover the biological mechanism underlying metastasis so we can finally understand how tumors shed cells, how the cells travel, how they survive, how they grow into new tumors, and how to stop them. In particular, we’re interested in how the local biological environment influences metastases that land in different parts of the body. Here’s a UCSF article a recent finding from my work: Metastatic Breast Cancer Cells Turn On Stem Cell Genes Here’s my lab at UCSF I’ll be back at 1 pm Et (10 am PT, 5 pm UTC) to answer your questions, ask me anything! EDIT: I am signed on. I am getting ready to answer questions. EDIT: Thanks for the questions. I am now signing off and getting back to research.

Hi reddit, thanks for visiting my AMA on marijuana today. I am currently doing research at McLean Hospital on marijuana as well as cigarettes. I thought reddit would be a good way to reach out to the community and answer any questions you may have regarding marijuana or addiction. I just recently released a book titled “Marijuana: The Unbiased Truth about the World’s Most Popular Weed” to dispel common myths people have on marijuana. With all the news lately regarding medical marijuana and legalization of marijuana, I think it is important for everyone to know the facts . I have a realistic view of the shift that is happening in this country and can answer any questions you have regarding the current state of marijuana laws in our country or marijuana itself. Some of my current studies involve new medications that have been used to treat marijuana addiction (yes reddit, it is addictive… not as much as other drugs, but that does not make it harmless). One of the medications we are currently using in a study is called Nabilone and chemically mimics the effects of THC. Feel free to ask me any questions about these new medications. Even though my focus recently has been more on marijuana, I have a lot of experience dealing with other addictions. I frequently visit news programs to discuss such things as the current opioid epidemic and how to treat opioid addiction. Check out my website: drkevinhill.com . There you can find more information about me as well as the research I am currently doing. If any of the studies sound like a good fit for you and you live in the Boston area, call the number on the website (617-855-2359) to participate. I will be back to answer your questions at 1 pm ET (10 am PT, 5 pm UTC), ask me anything! EDIT: Hey everyone. I am online and ready to tackle these questions over the next three hours. I am pumped by the number of questions you’ve already posted. Feel free to follow me on twitter @drkevinhill. To start, I just want to say that, while I have learned a lot about marijuana, mostly from my patients, I don’t have all of the answers. So if you have references to support statements that differ from mine, feel free to send them my way. UPDATE (3:20EST): Whew! I am wrapping up a few more questions, but thanks for joining us for a lively discussion. I will check back tomorrow to see if there are any pressing questions that people still want answers to. Otherwise, feel free to check out my website drkevinhill.com. I travel all over the country speaking on this important topic, so feel free to come say “hi” if I am in your area.

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