Abstract

Infectious diseases continue to pose a serious threat to human health as a result of the spread of antibiotic resistance, underscoring the urgent need for new and focused therapeutic approaches. Due to their regenerative and immunomodulatory capabilities, stem cells have emerged as a potential source for the development of antimicrobial therapies. This paper reviews the potential of stem cells as a targeted strategy for combating infections, focusing on their ability to differentiate into specific cell types that can directly target and eliminate microorganisms, as well as their capacity to modulate the immune response and enhance host defenses. The article discusses the challenges and opportunities associated with the clinical implementation of antimicrobial therapies derived from stem cells. Among these obstacles are the need for uniform protocols for cell isolation, expansion, and delivery, as well as the significance of rigorous evaluations of safety and efficacy. Given all relevant factors, it is our belief that the application of stem cells as a targeted antimicrobial approach holds significant potential for the development of effective and enduring therapeutic interventions for infectious diseases.